Procaine Penicillin G and Dihydrostreptomycin Sulphate Injection(20:20)

COMPOSITION

Contains per ml:

Procaine penicillin G 200 000 IU.

Dihydrostreptomycin sulphate 200 mg.

Solvents ad. 1 ml.

DESCRIPTION

The combination of procaine penicillin G and dihydrostreptomycin acts additive and in some cases synergistic. Procaine penicillin G is a small-spectrum penicillin with a bactericidal action against mainly Gram-positive bacteria like Campylobacter, Clostridium, Corynebacterium, Erysipelothrix, Haemophilus, Listeria, Pasteurella, penicillinase negative Staphylococcus and Streptococcus spp. Dihydrostreptomycin is an aminoglycoside with a bactericidal action against mainly Gram-negative bacteria like E. coli, Klebsiella, Pasteurella, Salmonella and Staphylococcus spp.

INDICATIONS

Arthritis, mastitis and gastrointestinal, respiratory and urinary tract infections caused by penicillin and dihydrostreptomycin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Klebsiella, Listeria, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp., in calves, cattle, goats, sheep and swine.

DOSAGE AND ADMINISTRATION

For intramuscular administration:

Cattle : 1 ml. per 20 kg. body weight for 3 days.

Calves, goats, sheep and swine : 1 ml. per 10 kg. body weight for 3 days.

Shake well before use and do not administer more than 20 ml. in cattle, more than 10 ml. in swine and more than 5 ml. in calves, sheep and goats per injection site.

CONTRAINDICATIONS

- Hypersensitivity to penicillin, procaine and/or aminoglycosides.

- Administration to animals with a serious impaired renal function.

- Concurrent administration with tetracyclines, chloramphenicol, macrolides and lincosamides.

SIDE EFFECTS

- Administration of therapeutic dosages of procaine penicillin G can result in abortion in sows.

- Ototoxity, neurotoxicity or nephrotoxicity.

- Hypersensitivity reactions.

WITHDRAWAL TIMES

- For kidney : 45 days.

- For meat : 21 days.

- For milk : 3 days.

WARING

Keep out of reach of children.

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