Tert-Butyl Carbazate CAS 870-46-2

Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.

Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.

Product Name:	Butylcarbazate BOC-hydrazide t-Butyloxycarbonyl-hydrazide Boc-hydrazine tert-Butoxycarbonylhydrazine tert-Butyl hydrazinocarboxylate tert.-Butylcarbazate Hydrazinoformic acid tert-butyl ester Hydrazine carboxylic acid T-butyl Tert-Butyloxycarbonyl-hydrazide Tert-Butoxycarbonyl Hydrazide tert-butyl hydrazinecarboxylate 1-tert-butylhydrazinecarboxylate
CAS:	870-46-2
EINECS:	212-795-3
MF:(molecular formula)	C5H12N2O2
MW:(molecular weight)	131.154
MOL File:	870-46-2.mol
InChIkey	DKACXUFSLUYRFU-UHFFFAOYSA-N
tert-Butyl carbazate CAS 870-46-2 Chemical Properties
Melting point	39-42 °C (lit.)
Boiling point	63-65 °C/0.1 mmHg (lit.)
Density	1.02g/mLat25°C(lit.)
Flashing point	92.994°C /197 °F
Water solubility	Soluble in ethanol and methanol.
Vapor pressure	0.024mmHg at 25°C
Refractive index	n20/D1.4496(lit.)(estimate)
Storage temp.	-20°C
Form	Crystalline Lumps
Color	White to slightly yellow
Sensitive	Moisture Sensitive
BRN	1756967
InChIKey	DYHSDKLCOJIUFX-UHFFFAOYSA-N
CAS DataBase Reference	870-46-2(CAS DataBase Reference)
EPA Substance Registry System	Hydrazinecarboxylic acid, 1,1-dimethylethyl ester (870-46-2)

 

Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 Advantages

● High purity >99%

● Stable supply capability: 1000tons/Year

● Standard packaging and storage

● Warranty: if there are quality problems, we can negotiate a refund or exchange

 

Colorless crystal, flammable, stored at 0~4℃.Phenyl chloroformate (C6H5OCOCl) is added dropwise to the mixed solution of tert-butanol, quinoline and dichloromethane (as solvent) to produce tert-butyl phenoxyformate [(CH3)3COCOOC6H5] first, which is then reacted with hydrazine to produce. It is used as a key intermediate in the production of tert-butyl azidocarboxylate.

Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 Application

Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 is a very important intermediate used in the synthesis of many tricyclic and above tricyclic compounds, and is widely used in the pharmaceutical, polymer compound and dye industries. In addition, Tert-Butyl carbazate is an important raw material for the synthesis of acyl hydrazinyl derivatives.

● Employed in a palladium-catalyzed cross-coupling with vinyl halides leading to N-Boc-N-alkenylhydrazines.
● Reagent used in solid phase peptide synthesis and in α-amino aldehyde optical purity determinations. Condenses with aldehydes to form hydrazones which are intermediates in the synthesis of HIV-1 protease inhibitors.

● Synthesis of amino acid protectants

● Raw material for the preparation of BOC-azide, a reagent for introducing BOC amino acid protection.

● Also used as a reagent for synthesizing sulfonyl hydrazides and carboxy hydrazides.

● Used in palladium-catalyzed cross-coupling reactions with vinyl halides

● to produce N-tert-butoxycarbonyl-N-alkenyl hydrazine.

● Reagent for solid-phase peptide synthesis and optical purity determination of alpha-amino aldehydes.

● Can be condensed with aldehydes to form hydrazones, which can be used as intermediates in the synthesis of HIV-1 protease inhibitors

 

Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 Safety Instructions:

● Dangerous Goods Marking T-F,T,F

● Hazard Class Code48-36/37/38-24/25-11

● Safety Description45-36/37/39-16-24/25Chemicalbook

● Dangerous Goods Transport Number 1325

● WGK Germany 3

● F21

● TSCA Yes

● HazardClass 4.1

● PackingGroupIII

● S16 - Keep away from sources of ignition.

● S36/37/39 - Wear appropriate protective clothing, gloves and goggles or mask.

● S45 - In case of accident or discomfort, seek immediate medical attention (if possible, show its label).

 

Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 Risk Terms

● R11 - Highly flammable.

● R36/37/38 - Irritates eyes, respiratory system and skin.

● R48 - Serious health hazard from prolonged exposure.

Export Market(Overseas Market)

● Main markets

● North America includes the United States, Canada, and Mexico

● Europe includes Belgium, Germany, France, UK, Italy, Spain

● South America includes Colombia, Argentina, Brazil, and Chile

● The Asia Pacific includes Japan, China, Korea, India, Saudi Arabia, and Southeast Asia

● What exhibitions have we participated

● API 2017 2018 2019 2022 online, China,Germany, Japan

 

Boze Chemical service

-Our Policy "We care quality, we care life"

-Delivery: By air or sea  (DHL, UPS, FeDex, TNT...)

-Warranty information: if there are quality problems, we can negotiate a refund or exchange

 

Payment method

● TT/ LC/Paypal,Western Union...

 

Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 Packing

In 25kgs or 30kgs net plastic drum, or steel drum, according to customer’s requests.

 

Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 Transport

Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 Storage    

● Store in freezer, under -20°C.

● Keep in dark place, Inert atmosphere

 

Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 Precautious:

P240 : Ground/bond container and receiving equipment.
P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking.
P241 : Use explosion-proof electrical/ ventilating/ lighting/ equipment.
P280 : Wear protective gloves/ eye protection/ face protection.
P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.

Store in a cool place. Incompatible with strong oxidizing agents and strong bases.

 

Tert-Butyl Carbazate(BOC Hydrazine)CAS:870-46-2 is an organic compound that belongs to the class of trifluoroacetic acids. It has been shown to inhibit the Mcl-1 protein, which is a key regulator of mitochondrial membrane potential and is involved in cell death. Tert-Butyl carbazate also inhibits the growth of K562 cells by binding to their nucleic acids. The reaction solution containing tert-butyl carbazate was found to be more effective at inhibiting inulin uptake than a solution containing a different trifluoroacetic acid. This could be because it inhibits the biological function of inulin, which is the transport of glucose across cell membranes.

 

BZ Chemical frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.If you want to konw more information,please click on the "CONTACT US" button.We will give you a professional answer for your question.